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PAST WORK

Past Work

 A small selection of my previous work is featured below.

EDUCATION

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Projected Graduation 2024

Indiana University School of Medicine

Doctor of Philosophy

2016

Loyola University

Master of Science: Molecular Biology

2011

University of Mississippi

Bachelor of Science: Biology

GRANTS & AWARDS

2023

NIH T32 Institutional Training Grant (NIH T32 5T32AI060519): January 2023- Present

AAI Trainee Abstract Award: May 2023

2022

IUPUI Graduate Student Travel Fellowship- $800 for travel to “The Human Microbiome: Ecology and Evolution” Keystone Symposium: December 2022

Publications

PUBLICATIONS

Bloodworth, J.C., Hoji, A., Wolff, G., Mandal, R.K., Schmidt, N.W., Deshane, J.S., Morrow, C.D., Kloepfer, K.M., Cook-Mills, J.M. (2023). Dysbiotic lung microbial communities of neonates from allergic mothers confer neonate responsiveness to suboptimal allergen. Front Allergy, Mar 10;4:1135412. doi: 10.3389/falgy.2023.1135412. PMID: 36970065; PMCID: PMC10036811.

Cabanov, A., Flood, B. A., Bloodworth, J. C., Higgs, E. F., Fessler, J., Leung, M. Y. K., Cron, K. R., Trujillo, J., Pyzer, A. R., Rouhani, S., Strohbehn, G., Heiss, B., Ratain, M., Reid, P., Yeo, K. J., Sweis, R. F., Zha, Y., Gajewski, T. F. (2020) Abstract S04-02: Treatment with tocilizumab does not inhibit induction of anti-COVID-19 antibodies in patients with severe SARS-CoV-2 infection. Clinical Cancer Research, (26) (18 Supplement) S04-02; DOI: 10.1158/1557-3265. COVID-19-S04-02

Strohbehn, G. W., Heiss, B. L., Rouhani, S. J., Trujillo, J. A., Yu, J., Kacew, A. J., Higgs, E. F., Bloodworth. J. C., Cabanov, A., Wright, R. C., Koziol, A. K., Weiss, A., Danahey, K., Karrison, T. G., Edens, C. C., Bauer, Ventura, I., Pettit, N. N., Patel, B. K., Pisano, J., Strek, M. E., Gajewski, T. F., Ratain, M. J., Reid, P. D. (2021). COVIDOSE: A Phase II Clinical Trial of Low-Dose Tocilizumab in the Treatment of Noncritical COVID-19 Pneumonia. Clinical Pharmacology & Therapeutics, 109 (3):688-696. doi: 10.1002/cpt.2117. Epub 2020 Dec 10. PMID: 33210302; PMCID: PMC7753375.

Andolfi, C., Bloodworth, J. C., Papachristos, A., Sweis, R. F. (2020). The Urinary Microbiome and Bladder Cancer: Susceptibility and Immune Responsiveness. Bladder Cancer, 6(3):225-235. doi: 10.3233/BLC-200277. PMID: 33195783; PMCID: PMC7605348.

Sweis, R. F., Golan, S., Barashi, N., Hill, E., Andolfi, C., Werntz, R. P., Bloodworth, J. C., Steinberg, G. D. (2019). Association of the commensal urinary microbiome with response to Bacillus Calmette-Guérin (BCG) immunotherapy in nonmuscle invasive bladder cancer. Journal of Clinical Oncology, 37(7_suppl), 423-423. doi:10.1200/jco.2019.37.7_suppl.423

Higgs, E. F., Flood, B. A., Pyzer, A. R., Rouhani, S.J., Trujillo J. A., Cron, K. R., Cabanov, A., Fessler, J., Bloodworth. J. C., Beavis, K., Yeo, K. J., Sweis, R. F., Zha, Y., Gajewski, T. F. (2020) Abstract PO-067: Tissue banking from patients with SARS-CoV-2 (COVID-19) infection. Clinical Cancer Research, (26) (18 Supplement) PO-067; DOI: 10.1158/1557-3265.COVID-19-PO-067

Shah, N., Kumar, S., Zaman, N., Pan, C.C., Bloodworth, J.C., Lei, W., Streicher, J. M., Hempel, N., Mythreye, K., Lee, N. Y. (2018). TAK1 activation of alpha-TAT1 and microtubule hyperacetylation control AKT signaling and cell growth. Nature Communications, 27;9(1):1696. doi: 10.1038/s41467-018-04121-y.

Bloodworth J.C., Osipo C. (2018) The Role of Notch in Breast Cancer. In: Miele L., Artavanis-Tsakonas S. (eds) Targeting Notch in Cancer. Springer, New York, NY

Pandya, K., Wyatt, D., Gallagher, B., Shah, D., Baker, A., Bloodworth, J. C., Zlobin. A., Pannuti, A., Green. A., Ellis, I.O., Filipovic, A., Sagert, J., Rana. A., Albain, K.S., Miele, L., Denning, M. F., Osipo, C. (2015). PKC  Attenuates Jagged-1-Mediated Notch Signaling in ErbB-2-Positive Breast Cancer to Reverse Trastuzumab Resistance. Clinical Cancer Research, 22(1), 175-186. doi:10.1158/1078-0432.ccr-15-0179

Kumar, S., Pan, C. C., Bloodworth, J. C., Nixon, A. B., Theuer, C., Hoyt, D. G., & Lee, N. Y. (2013). Antibody-directed coupling of endoglin and MMP-14 is a key mechanism for endoglin shedding and deregulation of TGF-β signaling. Oncogene, 33(30), 3970-3979. doi:10.1038/onc.2013.386

Zlobin, A., Wyatt, D., Bloodworth, J. C., Hilsenbeck, S., Fuqua, S., Miele, L., Albain, K. S., Osipo, C. (2016). Abstract LB-121: DAXX is a novel Notch-1 gene target and biomarker of GSI-sensitivity in ER breast cancer. Cancer Research, 76(14 Supplement). doi:10.1158/1538-7445.am2016-lb-121

Pan, C. C., Kumar, S., Shah, N., Bloodworth, J. C., Hawinkels, L. J., Mythreye, K., Hoyt, D. G. Lee, N. Y. (2015). Endoglin Regulation of Smad2 Function Mediates Beclin1 Expression and Endothelial Autophagy. Journal of Biological Chemistry, 290(24), 14884-14892. doi:10.1074/jbc.m114.630178

Pan, C. C., Bloodworth, J. C., Mythreye, K., & Lee, N. Y. (2012). Endoglin inhibits ERK-induced c-Myc and cyclin D1 expression to impede endothelial cell proliferation. Biochemical and Biophysical Research Communications, 424(3), 620-623. doi:10.1016/j.bbrc.2012.06.163

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