CURRENT WORK
A selection of my current work is featured below.
PAST WORK
A small selection of my previous work is featured below.
EDUCATION
Projected Graduation 2025
Indiana University School of Medicine
Doctor of Philosophy
2016
Loyola University
Master of Science: Molecular Biology
2011
University of Mississippi
Bachelor of Science: Biology
PUBLICATIONS
Sweis, R. F., Golan, S., Barashi, N., Hill, E., Andolfi, C., Werntz, R. P., Bloodworth, J. C., Steinberg, G. D. (2019). Association of the commensal urinary microbiome with response to Bacillus Calmette-Guérin (BCG) immunotherapy in nonmuscle invasive bladder cancer. Journal of Clinical Oncology,37(7_suppl), 423-423. doi:10.1200/jco.2019.37.7_suppl.423
Shah, N., Kumar, S., Zaman, N., Pan, C.C., Bloodworth, J.C., Lei, W., Streicher, J. M., Hempel, N., Mythreye, K., Lee, N. Y. (2018). TAK1 activation of alpha-TAT1 and microtubule hyperacetylation control AKT signaling and cell growth. Nature Communications, 27;9(1):1696. doi: 10.1038/s41467-018-04121-y.
Pandya, K., Wyatt, D., Gallagher, B., Shah, D., Baker, A., Bloodworth, J. C., Zlobin. A., Pannuti, A., Green. A., Ellis, I.O., Filipovic, A., Sagert, J., Rana. A., Albain, K.S., Miele, L., Denning, M. F., Osipo, C. (2015). PKC Attenuates Jagged-1-Mediated Notch Signaling in ErbB-2-Positive Breast Cancer to Reverse Trastuzumab Resistance. Clinical Cancer Research, 22(1), 175-186. doi:10.1158/1078-0432.ccr-15-0179
Kumar, S., Pan, C. C., Bloodworth, J. C., Nixon, A. B., Theuer, C., Hoyt, D. G., & Lee, N. Y. (2013). Antibody-directed coupling of endoglin and MMP-14 is a key mechanism for endoglin shedding and deregulation of TGF-β signaling. Oncogene, 33(30), 3970-3979. doi:10.1038/onc.2013.386
Bloodworth J.C., Osipo C. (2018) The Role of Notch in Breast Cancer. In: Miele L., Artavanis-Tsakonas S. (eds) Targeting Notch in Cancer. Springer, New York, NY
Zlobin, A., Wyatt, D., Bloodworth, J. C., Hilsenbeck, S., Fuqua, S., Miele, L., Albain, K. S., Osipo, C. (2016). Abstract LB-121: DAXX is a novel Notch-1 gene target and biomarker of GSI-sensitivity in ER breast cancer. Cancer Research, 76(14 Supplement). doi:10.1158/1538-7445.am2016-lb-121
Pan, C. C., Kumar, S., Shah, N., Bloodworth, J. C., Hawinkels, L. J., Mythreye, K., Hoyt, D. G. Lee, N. Y. (2015). Endoglin Regulation of Smad2 Function Mediates Beclin1 Expression and Endothelial Autophagy. Journal of Biological Chemistry, 290(24), 14884-14892. doi:10.1074/jbc.m114.630178
Pan, C. C., Bloodworth, J. C., Mythreye, K., & Lee, N. Y. (2012). Endoglin inhibits ERK-induced c-Myc and cyclin D1 expression to impede endothelial cell proliferation. Biochemical and Biophysical Research Communications, 424(3), 620-623. doi:10.1016/j.bbrc.2012.06.163
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