PAST WORK

 A small selection of my previous work is featured below.

 

EDUCATION

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Projected Graduation 2025

Indiana University School of Medicine

Doctor of Philosophy

2016

Loyola University

Master of Science: Molecular Biology

2011

University of Mississippi

Bachelor of Science: Biology

 

Strohbehn, G. W., Heiss, B. L., Rouhani, S. J., Trujillo, J. A., Yu, J., Kacew, A. J., Higgs, E. F., Bloodworth. J. C., Cabanov, A., Wright, R. C., Koziol, A. K., Weiss, A., Danahey, K., Karrison, T. G., Edens, C. C., Bauer, Ventura, I., Pettit, N. N., Patel, B. K., Pisano, J., Strek, M. E., Gajewski, T. F., Ratain, M. J., Reid, P. D. (2021). COVIDOSE: A Phase II Clinical Trial of Low-Dose Tocilizumab in the Treatment of Noncritical COVID-19 Pneumonia. Clinical Pharmacology & Therapeutics, 109 (3):688-696. doi: 10.1002/cpt.2117. Epub 2020 Dec 10. PMID: 33210302; PMCID: PMC7753375.

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PUBLICATIONS

Cabanov, A., Flood, B. A., Bloodworth, J. C., Higgs, E. F., Fessler, J., Leung, M. Y. K., Cron, K. R., Trujillo, J., Pyzer, A. R., Rouhani, S., Strohbehn, G., Heiss, B., Ratain, M., Reid, P., Yeo, K. J., Sweis, R. F., Zha, Y., Gajewski, T. F. (2020) Abstract S04-02: Treatment with tocilizumab does not inhibit induction of anti-COVID-19 antibodies in patients with severe SARS-CoV-2 infection. Clinical Cancer Research, (26) (18 Supplement) S04-02; DOI: 10.1158/1557-3265. COVID-19-S04-02

Sweis, R. F., Golan, S., Barashi, N., Hill, E., Andolfi, C., Werntz, R. P., Bloodworth, J. C., Steinberg, G. D. (2019). Association of the commensal urinary microbiome with response to Bacillus Calmette-Guérin (BCG) immunotherapy in nonmuscle invasive bladder cancer. Journal of Clinical Oncology, 37(7_suppl), 423-423. doi:10.1200/jco.2019.37.7_suppl.423

Shah, N., Kumar, S., Zaman, N., Pan, C.C., Bloodworth, J.C., Lei, W., Streicher, J. M., Hempel, N., Mythreye, K., Lee, N. Y. (2018). TAK1 activation of alpha-TAT1 and microtubule hyperacetylation control AKT signaling and cell growth. Nature Communications, 27;9(1):1696. doi: 10.1038/s41467-018-04121-y.

Pandya, K., Wyatt, D., Gallagher, B., Shah, D., Baker, A., Bloodworth, J. C., Zlobin. A., Pannuti, A., Green. A., Ellis, I.O., Filipovic, A., Sagert, J., Rana. A., Albain, K.S., Miele, L., Denning, M. F., Osipo, C. (2015). PKC  Attenuates Jagged-1-Mediated Notch Signaling in ErbB-2-Positive Breast Cancer to Reverse Trastuzumab Resistance. Clinical Cancer Research, 22(1), 175-186. doi:10.1158/1078-0432.ccr-15-0179

Kumar, S., Pan, C. C., Bloodworth, J. C., Nixon, A. B., Theuer, C., Hoyt, D. G., & Lee, N. Y. (2013). Antibody-directed coupling of endoglin and MMP-14 is a key mechanism for endoglin shedding and deregulation of TGF-β signaling. Oncogene, 33(30), 3970-3979. doi:10.1038/onc.2013.386

Andolfi, C., Bloodworth, J. C., Papachristos, A., Sweis, R. F. (2020). The Urinary Microbiome and Bladder Cancer: Susceptibility and Immune Responsiveness. Bladder Cancer, 6(3):225-235. doi: 10.3233/BLC-200277. PMID: 33195783; PMCID: PMC7605348.

Higgs, E. F., Flood, B. A., Pyzer, A. R., Rouhani, S.J., Trujillo J. A., Cron, K. R., Cabanov, A., Fessler, J., Bloodworth. J. C., Beavis, K., Yeo, K. J., Sweis, R. F., Zha, Y., Gajewski, T. F. (2020) Abstract PO-067: Tissue banking from patients with SARS-CoV-2 (COVID-19) infection. Clinical Cancer Research, (26) (18 Supplement) PO-067; DOI: 10.1158/1557-3265.COVID-19-PO-067

Bloodworth J.C., Osipo C. (2018) The Role of Notch in Breast Cancer. In: Miele L., Artavanis-Tsakonas S. (eds) Targeting Notch in Cancer. Springer, New York, NY

Zlobin, A., Wyatt, D., Bloodworth, J. C., Hilsenbeck, S., Fuqua, S., Miele, L., Albain, K. S., Osipo, C. (2016). Abstract LB-121: DAXX is a novel Notch-1 gene target and biomarker of GSI-sensitivity in ER breast cancer. Cancer Research, 76(14 Supplement). doi:10.1158/1538-7445.am2016-lb-121

Pan, C. C., Kumar, S., Shah, N., Bloodworth, J. C., Hawinkels, L. J., Mythreye, K., Hoyt, D. G. Lee, N. Y. (2015). Endoglin Regulation of Smad2 Function Mediates Beclin1 Expression and Endothelial Autophagy. Journal of Biological Chemistry, 290(24), 14884-14892. doi:10.1074/jbc.m114.630178

Pan, C. C., Bloodworth, J. C., Mythreye, K., & Lee, N. Y. (2012). Endoglin inhibits ERK-induced c-Myc and cyclin D1 expression to impede endothelial cell proliferation. Biochemical and Biophysical Research Communications, 424(3), 620-623. doi:10.1016/j.bbrc.2012.06.163